Severe Retinal Whitening in an Adult with Cerebral Malaria
نویسندگان
چکیده
881 * Address correspondence to Richard J. Maude, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 3/F, 60th Anniversary Chalermprakiat Building, 420/6 Rajvithi Road, Rajthevee, Bangkok 10400, Thailand. E-mail: [email protected] or [email protected] Images in Clinical Tropical Medicine Severe Retinal Whitening in an Adult with Cerebral Malaria
منابع مشابه
Reversibility of Retinal Microvascular Changes in Severe Falciparum Malaria
Malarial retinopathy allows detailed study of central nervous system vascular pathology in living patients with severe malaria. An adult with cerebral malaria is described who had prominent retinal whitening with corresponding retinal microvascular obstruction, vessel dilatation, increased vascular tortuosity, and blood retinal barrier leakage with decreased visual acuity, all of which resolved...
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Cerebral malaria (CM), a complication of malaria infection, is the cause of the majority of malaria-associated deaths in African children. The standard clinical case definition for CM misclassifies ~25% of patients, but when malarial retinopathy (MR) is added to the clinical case definition, the specificity improves from 61% to 95%. Ocular fundoscopy requires expensive equipment and technical e...
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BACKGROUND The diagnosis of cerebral malaria is problematic in malaria-endemic areas because encephalopathy in patients with parasitemia may have another cause. Abnormal retinal findings are thought to increase the specificity of the diagnosis, and the level of histidine-rich protein 2 (HRP2) may reflect the parasite biomass. METHODS We examined the retina and measured plasma HRP2 levels in c...
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Cerebral malaria is one of the most serious manifestations of severe malaria in adults. The exact pathophysiology of the disease, however, is still elusive. The ocular fundus findings are supposed to reflect the pathological changes taking place in the cerebral tissue. In about 15% patients of cerebral malaria, retinal hemorrhages are seen1. They are multiple and bilateral, and the most common ...
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